324+ Panama Holiday Rentals & Private Villas

Find Family-Friendly Holiday Rentals in or near Panama

Discover more than 324 holiday rentals in Panama. Rent By Owner holiday homes has everything you need to find a place to stay near Panama, .

Whether you are looking for luxury villas in Panama, furnished homes, unique style condos, flats, cozy cottages for a romantic getaway, spacious apartment for family holidays, or stylish accommodation for a business trip, we can help you find the perfect place. Our holiday rentals include top amenities such as indoor/outdoor swimming pools, kitchen facilities, gyms, hot tubs, Internet connectivity, and more.

If you are planning to travel to Panama with a whole family or group, RBO holiday accommodations make your trip memorable. We have plenty of places to stay in Panama for families, large parties, or private owner accommodations for long or short trips. Panama Pet-friendly holiday rentals are available. Book your favorite vacation rentals in Panama with Rent By Owner. RBO makes it easy to compare and book holiday rentals today.

Show more
Show less

Frequently Asked Questions About Panama Holiday Rentals

There are a lot of options in Panama. If you plan on staying in the Panama area, consider making a reservation for a few nights at one of these properties as these have been rated the top Holiday Home Rentals in Panama:

There are many holiday rentals available in Panama; however, here are a few of the most popular holiday homes listed in Panama on our website:
At Rent By Owner most of our places to stay are perfect for families. Check out the complete list of holiday homes in Panama to find one that works for you.
Yes, there are 324 self-catering family homes and holiday rentals in Panama.
There are more than 324 luxury holiday homes in or near Panama, according to 2025 data from Rent By Owner. Consider these homes for your next holiday: